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Clostridium difficile

C. difficile increases mortality, colectomy, complication risk in UC

Healio - ‎17 hours ago‎
Clostridium difficile infection results in a poorer prognosis among patients newly diagnosed with ulcerative colitis, as it increases their risk for colectomy, postoperative complications and death, according to a population-based inception cohort study.

Isolation of Clostridium difficile-carriers linked to lower hospital transmission

2 Minute Medicine - ‎Apr 26, 2016‎
1. Screening for and isolating carriers of Clostridium difficile at admission to hospital was associated with lower rates of healthcare-associated C. difficile infection (HA-CDI) at a single institution in Quebec, CA. 2. A multi-center study would be ...

Effort to detect, isolate asymptomatic C. difficile carriers linked to lower incidence

Science Daily - ‎Apr 25, 2016‎
An intervention at a Canadian acute care facility to screen and isolate asymptomatic Clostridium difficile carriers was associated with decreased incidence of health-care associated C. difficile infection, a finding that needs to be confirmed in ...

Isolating Asymptomatic C diff Carriers May Reduce Incidence

Medscape - ‎Apr 26, 2016‎
Screening for and isolating asymptomatic Clostridium difficile carriers appears to have cut the number of infections in half at the Heart and Lung Institute, a 354-bed Canadian tertiary institution in Québec City, Québec, Canada, researchers say.

Inhibitory Activity of Systemic Antibiotics Against Clostridium difficile

Infection Control Today - ‎Apr 20, 2016‎
Systemic antibiotics vary widely in in vitro activity against Clostridium difficile. Some agents with activity against C. difficile (e.g., piperacillin/tazobactam) inhibit establishment of colonization in mice. Kundrapu, et al. (2016) tested the ...

Secondary bile salts may be novel biomarkers of C. difficile recurrence

Healio - ‎Apr 26, 2016‎
Patients with recurrent Clostridium difficile infection had distinct bile acid and microbiome profiles compared with healthy controls and patients with first Clostridium difficile infection, according to research published in Alimentary Pharmacology ...

Detecting, isolating C. difficile carriers associated with reduced incidence of hospital-acquired infections

Healio - ‎Apr 27, 2016‎
Screening and isolating asymptomatic Clostridium difficile carriers was associated with lower incidence of health care-associated C. difficile infections at an acute care facility in Canada, according to research published in JAMA Internal Medicine.

Detecting, Isolating C. difficile Carriers Beneficial

Doctors Lounge - ‎Apr 26, 2016‎
Detecting and isolating Clostridium difficile carriers can reduce the incidence of health care-associated C. difficile infection, according to a study published online April 25 in JAMA Internal Medicine.

Probiotika og tilførte tarmbakterier kan forebygge infeksjon

Nasjonalt kunnskapssenter for helsetjenesten - ‎Apr 27, 2016‎
Bakterien Clostridium difficile er en av de hyppigste årsakene til sykehusrelatert diaré. Symptomene skyldes endringer av tarmens normale bakterieflora på grunn av antibiotikabehandling.

Report: Antibiotic stewardship programs lower infections, improve care

CIDRAP - ‎18 hours ago‎
Vibra Hospital of Northern California in Redding, Calif., and Sharp Villa Coronado Long-Term Care Facility in Coronado, Calif., were able to obtain support for nascent ASPs after linking antibiotic use to increases in healthcare-associated Clostridium ...

Impfung gegen Clostridium difficile

APOTHEKE ADHOC - ‎Apr 25, 2016‎
Krankenhauskeime sind ein zunehmendes Problem in den Industrieländern, da sich vermehrt Antibiotikaresistenzen entwickeln. Das anaerobe Bakterium C. difficile ist eine der Hauptursachen von Infektionen in Krankenhäusern und Pflegeeinrichtungen.

New study expands potential applications for stool transplants

Medical Xpress - ‎19 hours ago‎
The approach has been very successful for treating recurrent Clostridium difficile (C. diff) infections - which can cause life-threatening cases of diarrhoea, and are becoming a serious problem in hospitals and healthcare institutes.

Transplanted Fecal Microbes Stick Around

The Scientist - ‎20 hours ago‎
FMTs, in which stool microbes from a healthy donor are transplanted into a recipient, have been shown to be a successful treatment for recurrent Clostridium difficile infection, and are being investigated for a number of other gastrointestinal ...

News Scan for Apr 26, 2016

CIDRAP - ‎Apr 26, 2016‎
Screening patients at hospital admission for asymptomatic Clostridium difficile (C diff) and isolating those found to be carriers lowered the incidence of healthcare-associated C diff infection by more than 60% and may be a promising strategy for ...
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Summit Therapeutics PLC boosted by US patent for C-diff antibiotic

Proactive Investors USA & Canada - ‎Apr 28, 2016‎
Summit Therapeutics PLC (NASDAQ:SMMT, LON:SUMM) shares nudged higher in London as its new antibiotic for hospital superbug C.Diff got a further boost. The US patent and trademark office have granted a "composition of matter" patent. It gives a period ...

Mixed News on Hospital Infections

JAMA: The Journal of the American Medical Association - ‎Apr 26, 2016‎
Depending on the setting, antibiotic-resistant bacteria cause more than 1 in 4 health care–associated infections excluding C difficile, the investigators noted. They stressed that antibiotic stewardship programs are vital to preventing infections and ...

Meridian Bioscience Reports Drop in Q2 Revenues, Earnings

GenomeWeb - ‎22 hours ago‎
"Overall, diagnostics revenues declined due to competitive pressures in the C. difficile and foodborne segments," Kraeutler said.
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Special microbiome issue

Science Codex - ‎19 hours ago‎
Fecal transplants, where stool from a healthy donor is transplanted into the gut of another, have been shown to be beneficial for a range of diseases and particularly for treating Clostridium difficile infection. However, the microbiota dynamics ...
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Cedars-Sinai Scores a 'C' in Medical Center Safety Study

WEHOville - ‎Apr 28, 2016‎
Clostridium difficile infection. C. diff is a bacterium that can cause diarrhea, abdominal pain, loss of appetite, and fever, the Hospital Safety Score report says.

SMALL CAP MOVERS: Portable accommodation company Snoozebox warns sleepless nights not over after issuing ...

This is Money - ‎1 hour ago‎
Away from the miners, another company on the rise was Summit Therapeutics, which received a shot in the arm from the US patent and trademark office, after it granted a "composition of matter" patent to its C-Difficile treatment ridinilazole. Shares ...