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Clostridium difficile

C. difficile-associated reactive arthritis underdiagnosed, misdiagnosed among children

Healio - ‎May 25, 2016‎
“While the condition is documented in the published literature, the epidemiology of [Clostridium difficile infection-associated reactive arthritis (CDIAReA)] is poorly understood, both in adult and pediatric populations,” Daniel B. Horton, MD, MSCE, of ...

Ramizol®: A new treatment for Clostridium difficile associated disease Boulos and Cooper Pharmaceuticals Pty Ltd

EurekAlert (press release) - ‎May 18, 2016‎
The new antibiotic has low frequency of resistance and shows promise as a monotherapy for the treatment of Clostridium difficile associated disease. Dr Boulos stated "we are very excited about these results given the unforgiving nature of Clostridium ...

C difficile-Related Reactive Arthritis Misdiagnosed in Kids

Medscape - ‎May 17, 2016‎
Only 35% of cases of Clostridium difficile infection (CDI)-associated reactive arthritis in children were correctly diagnosed, a multicenter cohort and nested case-control study has found.

Ramizol drug shows promise in treatment of Clostridium difficile infections

News-Medical.net - ‎May 19, 2016‎
The new antibiotic has low frequency of resistance and shows promise as a monotherapy for the treatment of Clostridium difficile associated disease. Dr Boulos stated "we are very excited about these results given the unforgiving nature of Clostridium ...

HAI Prevalence Increased in Major Canadian Hospitals Due to C. difficile and Urinary Tract Infection

Infection Control Today - ‎May 25, 2016‎
According to Taylor, et al. (2016), in 2009, 9,953 acute care inpatients were surveyed; 1,234 infections (124/1000) were found, compared to 111/1000 in 2002, (p < 0.0001).

MODIFY: Bezlotoxumab prevents recurrent C. difficile infection in high-risk patients

Healio - ‎May 24, 2016‎
“[Bezlotoxumab] has been evaluated together with its partner, [actoxumab], which is an anti-A monoclonal antibody given to patients with Clostridium difficile infection in an attempt to prevent recurrences. It's given as ... a single IV infusion and ...

Global Clostridium difficile Infections (Clostridium difficile Associated Disease) Drugs and Companies Pipeline ...

NewsMaker (press release) - ‎May 25, 2016‎
The report provides comprehensive information on the therapeutics under development for Clostridium difficile Infections (Clostridium difficile Associated Disease), complete with analysis by stage of development, drug target, mechanism of action (MoA ...
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Swallowing human faeces will cure disease, NHS says

Telegraph.co.uk - ‎May 19, 2016‎
"Clostridium difficile is a disease people still underestimate," Dr Porter told The Times. "It has a huge impact.

Global Clostridium difficile Infections (Clostridium difficile Associated Disease) Therapeutics Pipeline Report 2016 ...

Business Wire (press release) - ‎May 16, 2016‎
This report provides comprehensive information on the therapeutic development for Clostridium difficile Infections (Clostridium difficile Associated Disease), complete with comparative analysis at various stages, therapeutics assessment by drug target, ...

Epidemiology of Clostridium difficile Infection-Associated Reactive Arthritis in Children: An Underdiagnosed ...

DG News - ‎May 18, 2016‎
Importance The incidence of Clostridium difficile infection has increased among children. The epidemiology of pediatric C difficile infection-associated reactive arthritis is poorly understood. Objective To characterize the incidence, recognition, and ...

Antibiotics after FMT increase long-term C. difficile recurrence rate

Healio - ‎May 22, 2016‎
SAN DIEGO - Patients who receive non-Clostridium difficile infection antibiotics after successful fecal microbiota transplantation therapy have a threefold increased rate of long-term CDI recurrence, according to data presented at DDW 2016.

Meta-Analysis: Probiotics Do Prevent C. Diff Infection

MedPage Today - ‎May 26, 2016‎
SAN DIEGO -- The use of probiotics was effective in preventing Clostridium difficile infection among high-risk hospitalized adults, a systematic review and meta-analysis found.

VIDEO: Bile salts predict recurrent C. difficile infection

Healio - ‎May 21, 2016‎
SAN DIEGO - In this exclusive video from DDW 2016, Jessica R. Allegretti, MD, MPH, from the Crohn's and Colitis Center and Harvard Medical School, Brigham and Women's Hospital, discusses her presentation on the potential of the secondary bile acid ...

Appili Therapeutics Inc. receives more than $3M in funding for C. difficile antibiotic

TheChronicleHerald.ca - ‎May 25, 2016‎
CEO Kevin Sullivan said the company will use the new investment to create a taste-masked, liquid treatment for C. difficile. The spore-forming bacterial infection is causing a big problem for people with weakened immune systems, including youth and ...
Appili Raises $3.2M in Seed Round

Fecal microbial transplants reduce antibiotic-resistant genes in patients with recurrent Clostridium difficile infection

Medical Xpress - ‎May 18, 2016‎
Clostridium difficile is a very common type of infection to which all of us are potentially exposed. However, some people find it harder to heal and traditional antibiotic treatments do not seem to have good results for everybody.

Global Clostridium difficile Partnering 2010 to 2016

PR Newswire (press release) - ‎May 16, 2016‎
NEW YORK, May 16, 2016 /PRNewswire/ -- The Global Therapy Partnering Terms and Agreements since 2010 report provides understanding and access to partnering deals and agreements entered into by the world's leading healthcare companies.

Pints, professors and poo: Science in the pub

ABC Online - ‎May 26, 2016‎
The University of Western Australia's Professor Tom Riley, an expert on pathology and laboratory medicine, takes the floor with his half hour presentation.
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Cameron pushes for action on 'superbugs'

Financial Times - ‎9 hours ago‎
... resistance], and the investment we make in doing so will be money well spent in saving lives.” An estimated 700,000 people a year are already dying worldwide from resistant strains of infectious diseases such as tuberculosis and Clostridium difficile.
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'Poop Transplant' Changes Play Out Over Several Months, Study Finds

Live Science - ‎May 23, 2016‎
Researchers analyzed the gut bacteria of eight patients who had Clostridium difficile, a difficult-to-treat bacterial infection that can be life-threatening.
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