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Colorectal cancer

Anti-colorectal cancer effect of interleukin-2 and interferon-β fusion gene driven by carcinoembryonic antigen promoter

Dove Medical Press - ‎May 30, 2016‎
Abstract: This study was designed to investigate the antitumor effects of combined interleukin-2/interferon-β-based gene therapy in colorectal cancer. Transfection of the fusion gene expression plasmid induced significant apoptosis of Lovo cells ...
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'Rapid increase' in colorectal cancers among young Canadians, study finds

CTV News - ‎May 26, 2016‎
Canadian doctors have observed a “rapid increase” in the number of patients under age 50 with colorectal cancers and they can't explain why.

3D hydrogel biochips offer better diagnosis of early-stage bowel cancer

Gizmag - ‎May 30, 2016‎
Early detection is paramount to survival from bowel cancer, but doing so is difficult because most symptoms don't present until the cancer matures.
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Colorectal Cancer on the Rise in Adults Under 50

Live Science - ‎May 24, 2016‎
SAN DIEGO - The number of U.S. adults who are diagnosed with colorectal cancer before age 50 is on the rise, a new study finds.
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Bowel cancer test: New 3D biochips diagnose bowel cancer in 95% of cases

International Business Times AU - ‎May 28, 2016‎
A hydrogel-based biochip with 3D cells may make bowel cancer detection easier, a study by scientists from the Moscow Institute of Physics and Technology (MIPT), the Engelhardt Institute of Molecular Biology (EIMB RAS) has suggested.

Blood Test Shows Promise as Colorectal Cancer Screen

MedPage Today - ‎May 25, 2016‎
SAN DIEGO -- A blood test that evaluates natural killer cell activity (NKA) showed high sensitivity and, consequently, high negative predictive value in screening patients at risk for colorectal cancer that could make it clinically useful if confirmed ...

Mitoxantrone for MS linked to colorectal cancer risk

News-Medical.net - ‎May 24, 2016‎
Treatment with mitoxantrone for multiple sclerosis (MS) carries only a mildly increased risk of malignancy overall, but the risk of colorectal cancer and leukaemia is heightened, researchers have found. They report a threefold increased incidence of ...

Study provides better understanding of sequence of genetic events in colorectal cancer premalignancy

News-Medical.net - ‎May 25, 2016‎
We have a comprehensive view of the genomic alterations of colorectal cancers, thanks to projects like The Cancer Genome Atlas (TCGA), but far less is known about the order in which these genomic alterations accumulate because the genomic landscapes ...
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Colon cancer rates on the rise among people under 50

CTV News - ‎May 25, 2016‎
"While the healthcare system has done a great deal to address colorectal cancer in people over 50 -- heightening patient awareness and increasing screenings -- our findings show that much more needs to be done to fight this cancer in people under 50, ...

HER2+ Colorectal Cancer: Slicing the CRC Pie into Curable Portions

Medscape - ‎May 23, 2016‎
There is a really cool study that just came out on HER2-positive colon cancer. We tried to do this 20 years ago, when trastuzumab first came out, and we said that there weren't enough HER2-positive patients out there.

Does ovary removal increase colorectal cancer risk?

ModernMedicine - ‎May 24, 2016‎
Women who have had their ovaries removed may be at increased risk of colorectal cancer as a result of alteration in sex hormone levels, according to a population analysis in British Journal of Surgery.
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Diet rich in fat, low in fibre linked to colorectal cancer

Times of India - ‎May 23, 2016‎
The earliest changes in normal colonic mucosa -- the first layer of the intestines where nutrients, fats and proteins are absorbed from the foods we eat -- has the potential to lead to the early detection and prevention of cancer development, the ...

Study Finds Uptick in Young-Onset Colon Cancer

MedPage Today - ‎May 24, 2016‎
SAN DIEGO -- Rates of colorectal cancer are on the rise among individuals younger than 50, a review of cases in the National Cancer Database found.
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Targeting ERK and compensatory pathways with drug inhibitors halts colorectal cancer growth

News-Medical.net - ‎May 18, 2016‎
While investigating a potential therapeutic target for the ERK1 and 2 pathway, a widely expressed signaling molecule known to drive cancer growth in one third of patients with colorectal cancer, University of California San Diego School of Medicine ...

Overweight patients less likely to die of colorectal cancer

Healio - ‎May 24, 2016‎
Patients categorized as underweight or class II to III obese at the time of and following diagnosis experienced an increased risk for all-cause mortality and colorectal cancer-specific mortality compared with participants categorized as having a normal ...

Body Mass Index Associated With Colorectal Cancer Mortality Risk

Cancer Therapy Advisor - ‎May 23, 2016‎
Body mass index (BMI) at the time of diagnosis and after diagnosis is associated with risk of death in patients with colorectal cancer, a study published in JAMA Oncology has shown.1. Although previous research has attempted to determine the ...

Black patients more likely to die of young-onset colorectal cancer

Healio - ‎May 19, 2016‎
“It is well known that there are racial disparities in colorectal cancer incidence and survival in the United States, but the reason for these differences remains unclear,” Elena M. Stoffel, MD, MPH, assistant professor of internal medicine at ...

Biomarker Indicates Which Patients With Colorectal Cancer Will Respond to Cetuximab

Oncology Nurse Advisor - ‎May 25, 2016‎
A blood-based test pinpoints which patients with metastatic colorectal cancer will benefit from treatment with cetuximab.1. Only approximately half of patients with incurable colorectal cancer benefit from cetuximab, and the reason behind its futility ...
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